Probiotics and PCOS

A small but well designed study in 2018 showed that probiotic supplementation can reduce total testosterone.

This study was 12 weeks long and it also showed that probiotics increase sex hormone binding globulin which can bind up testosterone reducing its’ effects on the body in PCOS (ie. acne hirsutism and hair loss)

Additionally, hs-crp, a marker of inflammation was reduced.

I often find a multistrain probiotic can work well here. Generally you want a probiotic to have lactobacillus and bifidobacterium and around 11-20 billion for a daily dose. Speak to your healthcare provider on which probiotic is best for you!

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Karamali M, Eghbalpour S, Rajabi S, Jamilian M, Bahmani F, Tajabadi-Ebrahimi M, Keneshlou F, Mirhashemi SM, Chamani M, Hashem Gelougerdi S, Asemi Z. (2018). Effects of Probiotic Supplementation on Hormonal Profiles, Biomarkers of Inflammation and Oxidative Stress in Women With Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Arch Iran Med, 1-7. PMID: 29664663.

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